Celsense Publications
Selected articles / abstracts using Celsense products:
2008
Basse-Luesebrink TC, Kampf T, Ziener CH, Klug G, Bauer WR, Jakob PM, Haddad D. Evaluation of sensitivity increase by T1 and T2 contrast agents in 19F MRI of PF15C. In: Proceedings of the 16th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Toronto, Ontario, Canada. Abstract #1655.
Hitchens TK, Ye Q, Zhang H, Foley LM, Janjic JM, Ahrens ET, Ho C. 19F MRI Detection of acute cardiac allograft rejection with in situ perfluorocarbon labeling of immune cells. In: Proceedings of the 16th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Toronto, Ontario, Canada. Abstract #1688.
Kampf T, Basse-Luesebrink TC, Weber M, Heymer A, Ebert R, Stoetzel C, Gbureck U, Noeth U, Jakob PM, Bauer WR, Haddad D. In vitro /in vivo MRI visualization of PFC/VSOP double-labeled mesenchymal stem cells. In: Proceedings of the 16th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Toronto, Ontario, Canada. Abstract #1692.
McConville P, Woolliscroft M, Mailliard R, Nelson A, Ahrens E, Barnard C, Mobley J, Cornicelli J. Imaging an inflammatory response using 19F-MRI. Inflamm Res 2008;57:S96-S96.
2009
Helfer BM, Nelson AD, Janjic JM, Ahrens ET, Kalinski P, de Vries J, Mailliard RB. In vivo cell tracking of immunotherapeutic cell types by fluorine MRI. In: Proceedings of the American Association for Cancer Research, Denver, Colorado, USA. Abstract #4312.
Helfer BM, Nelson AD, Janjic JM, Ahrens ET, Gil RR, Kalinski P, de Vries J, Mailliard RB. Using a 19F MRI tracer agent for in vivo tracking of human dendritic cell vaccines. In: Proceedings of the 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Honolulu, Hawaii, USA. Abstract #322.
Basse-Lüsebrink TC, Ladewig G, Kampf T, Melkus G, Haddad D, Bauer WR, Jakob PM, Stoll G. Multi-color 19F CSI: Simultaneous detection of differently labeled cells in vivo. In: Proceedings of the 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Honolulu, Hawaii, USA. Abstract #807.
Bonetto, FJ, Srinivas M, Heerschap A, Mailliard RB, Ahrens ET, Figdor C, de Vries J. Labeling of dendritic cells with a clinical applicable perfluorpolyether compound for quantitative 19F MRI tracking in cancer patients. In: Proceedings of the 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Honolulu, Hawaii, USA. Abstract #923.
Hitchens TK, Ye Q, Eytan DF, Wu YL, Janjic JM, Ahrens ET, Ho C. Comparison of iron-oxide- and perfluorocarbon-based cellular contrast agents for detecting immune cell infiltration in models of organ transplant rejection. In: Proceedings of the 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Honolulu, Hawaii, USA. Abstract #932.
Kaimal V, Monterosso T, Woolliscroft M, Cornicelli J, Mailliard RB, Ahrens ET, Nelson AD, Barnard C, Mobley J, McConville P. Imaging an inflammatory response in a sponge granuloma model using 19F-MRI. In: Proceedings of the 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Honolulu, Hawaii, USA. Abstract #2469.
Fischer André, Basse-Lüsebrink TC, Kampf T, Ladewig G, Blaimer M, Breuer FA, Stoll G, Bauer WR, Jakob PM. Improved sensitivity in 19F cellular imaging using nonconvex compressed sensing. In: Proceedings of the 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Honolulu, Hawaii, USA. Abstract #3154.
Klug G, Basse-Lüsebrink TC, Schnell C, Kampf T, Bauer E, Herold V, Parczyk M, Rommel E, Stoll G, Jakob PM, Bauer WR. 1H/19F molecular MR-imaging in mouse models of acute and chronic inflammation. In: Proceedings of the 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Honolulu, Hawaii, USA. Abstract #3172.
2010
Helfer BM, Nelson AD, Janjic JM, Gil RR, Kalinski P, de Vries J, Ahrens ET, Mailliard RB. Functional assessment of human dendritic cells labeledffor in vivo 19F magnetic resonance imaging cell tracking. Application of a novel 19F tracer agent for in vivo tracking of human dendritic cell vaccines. Cytotherapy 2010; 2010;12(2):238-250.
Foley LM, Hitchens TK, Melick JA, Ho C, Kochanck PM. 19F imaging assessment of labeled macrophage accumulation in a mouse brain following experimental traumatic brain injury. Proceedings of the 18th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Stockholm, Sweden. Abstract #5703.
Selected background references for 19F cell tracking using various emulsion technologies:
Ahrens ET, Flores R, Xu H, Morel PA. In vivo imaging platform for tracking immunotherapeutic cells. Nat Biotechnol 2005;23(8):983-987.
Srinivas M, Morel PA, Ernst LA, Laidlaw DH, Ahrens ET. Fluorine-19 MRI for visualization and quantification of cell migration in a diabetes model. Magn Reson Med 2007;58:725–734.
Partlow KC, Chen J, Brant JA, Neubauer AM, Meyerrose TE, Creer MH, Nolta JA, Caruthers SD, Lanza GM, Wickline SA. 19F magnetic resonance imaging for stem/progenitor cell tracking with multiple unique perfluorocarbon nanobeacons. FASEB J 2007;21(8):1647-1654.
Janjic JM, Srinivas M, Kadayakkara DKK, Ahrens ET. Self-delivering nanoemulsions for dual fluorine-19 MRI and fluorescence detection. J Am Chem Soc 2008;130(9):2832-2841.
Flogel U, Ding Z, Hardung H, Jander S, Reichmann G, Jacoby C, Schubert R, Schrader J. In vivo monitoring of inflammation after cardiac and cerebral ischemia by fluorine magnetic resonance imaging. Circulation 2008;118(2):140-148.
Ruiz-Cabello J, Walczak P, Kedziorek DA, Chacko VP, Schmieder AH, Wickline SA, Lanza GM, Bulte JWM. In vivo "hot spot" MR imaging of neural stem cells using fluorinated nanoparticles. Magn Reson Med 2008;60(6):1506-1511.
Janjic JM, Ahrens ET. Fluorine-containing nanoemulsions for MRI cell tracking. WileyInterdiscip Rev Nanomed Nanobiotechnol. 2009 1(5):492-501.
Srinivas, M, Turner, MS, Janjic JM, Morel, PA, Laidlaw, DH, Ahrens, ET. In vivo cytometry of antigen specific T-cells using 19F MRI. Magn Reson Med 2009;62(3):747-753.
Behm P, Burghoff JC, French BA, Schrader J, Flogel U. Early assessment of pulmonary inflammation by 19F MRI in vivo. Circ Cardiovasc Imaging 2010;3(2):202-210.
Kadayakkara DK, Beatty PL, Turner MS, Janjic JM, Ahrens ET, Finn OJ. Inflammation driven by overexpression of the hypoglycosylated abnormal mucin 1 (MUC1) links inflammatory bowel disease and pancreatitis. Pancreas 2010;39(4):510-515.