Celsense - Cell Sense & Cell Tracking Papers



Cell Sense & Cell Tracking - Papers

19F-MRI for monitoring human NK cells in vivo. Bouchlaka, Myriam N., Kai D. Ludwig, Jeremy W. Gordon, Matthew P. Kutz, Bryan P. Bednarz, Sean B. Fain, and Christian M. Capitini. Oncoimmunology 5, no. 5 (2016): e1143996.

In-Vivo Detection and Tracking of T Cells in Various Organs in a Melanoma Tumor Model by 19 F-Fluorine MRS/MRI. Gonzales, Christine, Hikari AI Yoshihara, Nahzli Dilek, Julie Leignadier, Melita Irving, Pascal Mieville, Lothar Helm, Olivier Michielin, and Juerg Schwitter. PloS one 11, no. 10 (2016): e0164557.

Application of dual 19F and iron cellular MRI agents to track the infiltration of immune cells to the site of a rejected stem cell transplant. Gaudet, Jeffrey M., Amanda M. Hamilton, Yuanxin Chen, Matthew S. Fox, and Paula J. Foster. Magnetic Resonance in Medicine (2016).

In Vivo 19 F-Magnetic Resonance Imaging of Adoptively Transferred NK Cells. Somanchi, Srinivas S., Bridget A. Kennis, Vidya Gopalakrishnan, Dean A. Lee, and James A. Bankson. Natural Killer Cells: Methods and Protocols (2016): 317-332.

Cellular Imaging with MRI. Makela, Ashley V., Donna H. Murrell, Katie M. Parkins, Jenna Kara, Jeffrey M. Gaudet, and Paula J. Foster. Topics in Magnetic Resonance Imaging 25, no. 5 (2016): 177-186.

Clinical cell therapy imaging using a perfluorocarbon tracer and fluorine‐19 MRI. Ahrens, E. T., Helfer, B. M., O’Hanlon, C. F., & Schirda, C. (2014). Magnetic Resonance in Medicine, 72(6), 1696-1701.

Tracking the Fate of Stem Cell Implants with Fluorine-19 MRI. Gaudet, J. M., Ribot, E. J., Chen, Y., Gilbert, K. M., & Foster, P. J. (2015). PloS one, 10(3), 0118544.

Fluorine-19 Labeling of Stromal Vascular Fraction Cells for Clinical Imaging Applications. Rose, L. C., Kadayakkara, D. K., Wang, G., Bar-Shir, A., Helfer, B. M., O’Hanlon, C. F., ... & Bulte, J. W. (2015). Stem cells translational medicine, sctm-2015.

Combining perfluorocarbon and superparamagnetic iron‐oxide cell labeling for improved and expanded applications of cellular MRI. Hitchens, T. K., Liu, L., Foley, L. M., Simplaceanu, V., Ahrens, E. T., & Ho, C. (2015). Magnetic Resonance in Medicine, 73(1), 367-375.

A multi-modality platform to image stem cell graft survival in the naïve and stroke-damaged mouse brain. Boehm-Sturm, P., Aswendt, M., Minassian, A., Michalk, S., Mengler, L., Adamczak, J., ... & Hoehn, M. (2014). Biomaterials, 35(7), 2218-2226.

Direct labeling of 19F-perfluorocarbon onto multilayered cell sheet for MRI-based non-invasive cell tracking. Oliva, J., Bardag-Gorce, F., Wood, A., Sota, H., & Niihara, Y. (2015). Tissue Engineering and Regenerative Medicine, 12(5), 371-378.

Combining perfluorocarbon and superparamagnetic iron-oxide cell labeling for improved and expanded applications of cellular MRI. Hitchens TK, Liu L, Foley LM, Simplaceanu V, Ahrens ET, Ho C. Magn Reson Med. 2014 Jan 29.

In vivo MR detection of fluorine-labeled human MSC using the bSSFP sequence. Ribot EJ, Gaudet JM, Chen Y, Gilbert KM, Foster PJ. Int J Nanomedicine. 2014 Apr 8;9:1731-9

Tracking immune cells in vivo using magnetic resonance imaging. Ahrens ET and Bulte JWM.  Nature Reviews|Immunology, 2013 October

In vivo MRI cell tracking using perfluorocarbon probes and fluorine-19 detection. Ahrens ET and Zhong J.  NMR in Biomedicine 2013 26: 860-971

A multi-modality platform to image stem cell graft survival in the naïve and stroke damaged mouse brain. Boehm-Sturm P, Aswendt M, Minassian A, Michalk S, Mengler L, Adamczak J, Mezzanotte L, Löwik A, and Hoehn M. Biomaterials (2013), http://dx.doi.org/10.1016/j.biomaterials.2013.11.085

Combining perfluorocarbon and superparamagnetic iron oxide cell labeling for improved and expanded applications of cellular MRI. Hitchens KT, Liu L, Foley L, Simplacaenu V, Ahrens ET, and Ho C.  Magnetic Resonance in Medicine 2013

Labeling cells for in vivo tracking using 19F MRI. Srinivas M, Boehm-Sturm P, Figdor CG, de Vries IJ, and Hoehn M.  Biomaterials 2012

Visualizing brain inflammation with a shingled-leg radio-frequency head probe for 19F/1H MRI.Waiczies H, Lepore S, Drechsler S, Qadri F, Purfurst B, Sydow K, Dathe M, Kuhne K, Lindel T, Hoffmann W, Pohlmann A, Niendorf T, and Waiczies S. Nature Scientific Reports 15 February 2013 3 : 1280 | DOI: 10.1038/srep01280

In vivo intracellular oxygen dynamics in murine brain glioma and immunotherapeutic response of cytotoxic T cells observed by fluorine-19 magnetic resonance Imaging. Zhong J, Sakaki M, Okada H, and Ahrens ET.  PLoS ONE 8(5): e59479. doi:10.1371/journal.pone.0059479

(19)F MRI tracer preserves in vitro and in vivo properties of hematopoietic stem cells. Helfer BM, Balducci A, Sadeghi Z, O’Hanlon C, Hijaz A, Flask CA, Wesa A. Cell Transplant. 2012 Aug 2.

Non-invasive imaging of transplanted human neural stem cells and ECM scaffold remodeling in the stroke-damaged rat brain by (19)F- and diffusion-MRI. Bible E, Dell’acqua F, Solanky B, Balducci A, Crapo PM, Badylak SF, Ahrens ET, Modo M. Biomaterials. 2012 Jan 12.

In vivo tracking of human neural stem cells with 19F magnetic resonance imaging. Boehm-Sturm P, Mengler L, Wecker S, Hoehn M, Kallur T, 2011. PLoS ONE 6(12): e29040.

A novel (19)F agent for detection and quantification of human dendritic cells using magnetic resonance imaging. Bonetto F, Srinivas M, Heerschap A, Mailliard R, Ahrens ET, Figdor CG, de Vries IJ. Int J Cancer. 2011 Jul 15;129(2):365-73.

Functional assessment of human dendritic cells labeled for in vivo (19)F magnetic resonance imaging cell tracking. Helfer BM, Balducci A, Nelson AD, Janjic JM, Gil RR, Kalinski P, de Vries IJ, Ahrens ET, Mailliard RB. Cytotherapy. 2010 Apr;12(2):238-50.

Inflammation driven by overexpression of the hypoglycosylated abnormal mucin 1 (MUC1) links inflammatory bowel disease and pancreatitis. Kadayakkara DK, Beatty PL, Turner MS, Janjic JM, Ahrens ET, Finn OJ. Pancreas. 2010 May;39(4):510-5.

In vivo observation of intracellular oximetry in perfluorocarbon-labeled glioma cells and chemotherapeutic response in the CNS using fluorine-19 MRI. Kadayakkara DK, Janjic JM, Pusateri LK, Young WB, Ahrens ET. Magn Reson Med. 2010 Nov;64(5):1252-9.

In vivo cytometry of antigen-specific t cells using 19F MRI. Srinivas M, Turner MS, Janjic JM, Morel PA, Laidlaw DH, Ahrens ET. Magn Reson Med. 2009 Sep;62(3):747-53.

Fluorine-19 MRI for visualization and quantification of cell migration in a diabetes model. Srinivas M, Morel PA, Ernst LA, Laidlaw DH, Ahrens ET. Magn Reson Med. 2007 Oct;58(4):725-34.

In vivo imaging platform for tracking immunotherapeutic cells. Ahrens ET, Flores R, Xu H, Morel PA. Nat Biotechnol. 2005 Aug;23(8):983-7


19F MRI cellular tracer preserves the differentiation potential of hematopoietic stem cells. Helfer B, Balducci A, Wesa A. 9th Annual Meeting of the International Society for Stem Cell Research, Toronto, Canada, June 15-18, 2011.

Labeling of T cells and NK cells with a clinically-applicable perfluorocarbon for quantitative 19F MRI tracking in cancer patients. Helfer B, Balducci A, Mailliard R, and Wesa A. 25th Annual Meeting of International Society for Biological Therapy of Cancer, Washington, DC; Oct 2-4, 2010.

Characterization of an F-19 MRI contrast agent in human NSCs for transplantation into stroked-lesioned brain. Bible E, Solanky B, Ahrens ET, Modo M. Cell Transplant 2010;19(3):331-331.

Clinically-compatible 19F NMR tracking of DC vaccines in vivo. Urban J, Helfer B, Thorne S, Ahrens E, Wesa A, Kalinski P. J Immunother 2010;33(8):880-880.

F19 Labeling of human alpha-type-1-polarized dendritic cells and standard dendritic cells for in vivo trafficking by fluorine MRI. Helfer BM, Balducci A, Mailliard R, Ahrens E, Kalinski P, Wesa A. J Immunother 2010;33(8):878-878.

In vitro / in vivo MRI visualization of PFC/VSOP double-labeled mesenchymal stem cells. Kampf T, Basse-Lüsebrink TC, Weber M, Heymer A, Ebert R, Stoetzel C, Gbureck U, Noeth U, Jakob PM, Bauer WR, Haddad D. In: Proceedings of the 16th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Toronto, Ontario, Canada. Abstract #1692.